Tuesday, July 8, 2025

DH25001 Lung Cancer Vaccine V01 080725

 A world-first lung cancer vaccine is now in human trials — and it could change everything.

Doctors have begun trialing the world’s first mRNA lung cancer vaccine across seven countries. 

The vaccine, known as BNT116 and developed by BioNTech, targets non-small cell lung cancer (NSCLC)—the most common and deadliest form of the disease. Using the same mRNA technology that powered COVID-19 vaccines, the jab trains the immune system to identify and destroy cancer cells while minimizing harm to healthy tissue. 

Early participants in the trial include 67-year-old Janusz Racz from London, who began treatment at University College London Hospitals.

The phase 1 trial will involve about 130 patients globally, including 20 in the UK, and marks a key step toward potentially making this therapy standard care. 

Delivered in weekly doses followed by maintenance injections, the vaccine is combined with immunotherapy to enhance the body’s anti-cancer defenses. Researchers hope this groundbreaking approach will not only treat existing tumors but also prevent recurrence — a major hurdle in lung cancer survival. 

If successful, future trial phases could usher in a new era of personalized cancer treatment and dramatically improve outcomes for millions worldwide.


🔗 Read more from University College London Hospitals: https://www.uclh.nhs.uk/news/first-uk-patient-receives-innovative-lung-cancer-vaccine


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